Can divalproex cause thrombocytopenia

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WebTake this medication by mouth as directed by your doctor. You may take it with food if stomach upset occurs. Swallow the tablet whole. Do not crush or chew the tablet, which … WebNov 2, 2024 · Along with its needed effects, divalproex sodium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need …

Would taking depakote cause both low platelets and low ... - HealthTap

WebMar 1, 2024 · Thrombocytopenia (low platelet count) or Viral infection (eg, HIV, cytomegalovirus infection)—Use with caution. May make these conditions worse. Liver disease or ... Divalproex sodium may cause serious allergic reactions affecting multiple … Divalproex sodium is used to treat certain types of seizures (epilepsy). This … WebThe phase IV clinical study analyzes which people take Depakote and have Thrombocytopenia. It is created by eHealthMe based on reports of 49,884 people who … tsa precheck 12 year old

The Risk of Thrombocytopenia During Valproic Acid …

WebSide Effects. See also Warning section. Diarrhea, dizziness, drowsiness, hair loss, blurred/ double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), … WebDec 30, 2024 · Valproic acid is a highly protein-bound drug. Serum levels of 50-100 mcg/mL are considered therapeutic, with minimal risk of toxicity when maintained within the … WebDec 19, 2024 · The exact mechanism through which valproate can cause thrombocytopenia is unknown; it can be caused by an increased disruption of platelets as well as by the formation of autoantibodies destroying platelets or by decreased production due to a direct toxic effect on bone marrow [ 3 ]. philly channels

Thrombocytopenia Guide: Causes, Symptoms and Treatment Options - Drugs.com

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WebDec 30, 2024 · It's likely that a routine blood test showing a high platelet count will be your first indication that you have thrombocytosis. Besides taking your medical history, examining you physically and running tests, your doctor might ask about factors that could affect your platelets, such as a recent surgery, a blood transfusion or an infection. WebJan 1, 2001 · Particular attention was paid to the dose and serum level of divalproex sodium coinciding with measurement of the hematologic parameters. Psychiatric diagnoses and medications, as well as general medical conditions and use of medications known to cause thrombocytopenia, were noted. tsa precheck accompanying passengerWebSep 23, 2010 · A positive finding provides very strong evidence that drug sensitivity is the cause of thrombocytopenia and can be helpful for understanding the mechanisms of DITP. 26 Because antibody testing is ordered only when a particular drug is suspected of being a possible cause of thrombocytopenia, identification of drug-dependent, platelet … tsa precheck advantages and disadvantages

"WebAug 22, 2013 · The case demonstrates thrombocytopenia induced by treatment with valproic acid in a relatively young patient after only a week of treatment. The risk of thrombocytopenia caused by valproic acid is 5%, and the risk increases with the age of the patient and with the level of valproic acid in the blood. 4-6 In this case, the patient was … " - Can divalproex cause thrombocytopenia

Can divalproex cause thrombocytopenia

Depakote and Depakote ER Side Effects: Mild, Severe, and More - Healthline

WebAug 17, 2024 · Bottom Line. Divalproex may be used for the treatment of absence or partial seizures, as a preventive treatment for migraine, and to treat mania associated with … WebThe table lists possible causes of isolated thrombocytopenia. Refer to the UpToDate topics on thrombocytopenia, immune thrombocytopenia, heparin-induced thrombocytopenia, and drug-induced thrombocytopenia for further details and a more complete list of drugs that can cause drug-induced thrombocytopenia. Graphic 77063 …

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WebAug 17, 2024 · Abdominal pain, nausea, vomiting, diarrhea, constipation, dyspepsia, dizziness, drowsiness, headache, fever, weakness, or weight loss. May also cause bleeding gums, bloating or swelling, cough, a tremor, hair loss, ataxia, nystagmus, a skin rash, somnolence, double vision, infection, and thinking difficulties. WebCommon causes of thrombocytopenia. Primary immune thrombocytopenia (ITP) Drug-induced immune thrombocytopenia (DITP) Heparin (NOTE: special case, also can …

WebNov 2, 2024 · Commonly reported side effects of divalproex sodium include: abdominal pain, asthenia, dizziness, drowsiness, nausea, vomiting, thrombocytopenia, and anorexia. Other side effects include: abnormality in thinking, alopecia, ataxia, nystagmus disorder, tremor, weight loss, fever, and skin rash. WebDrinking a lot of alcohol may cause your platelet level to drop. Toxic chemicals : Exposure to toxic chemicals, including arsenic, benzene and pesticides, may affect your platelet …

WebJun 27, 2024 · Unexplained thrombocytopenia is a common clinical problem, and the possibility of drug-induced thrombocytopenia must be considered, especially in … WebValproate can cause major congenital malformations, particularly neural tube defects (e.g., spina bifida). ... may be dose-related. The probability of thrombocytopenia appears to increase significantly at total valproate concentrations of ... Stopping divalproex sodium extended-release tablets suddenly can cause serious problems. Divalproex ...

WebMar 1, 2024 · Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches.

WebMethods: Patients with refractory partial epilepsy were enrolled in this double-blind, multicenter, concentration-response trial that evaluated the efficacy and safety of high … tsa precheck age limitWebNov 14, 2024 · Depakote (divalproex sodium) has many possible side effects. Some of the most common ones are stomach-related problems, headache, and drowsiness. More serious Depakote side effects include liver damage, birth defects, and pancreatitis. Talk to your healthcare provider about the risks and benefits of Depakote before you start it. tsa precheck ageWebApr 19, 2024 · Thrombocytopenia rarely is inherited; or it can be caused by a number of medications or conditions. Whatever the cause, circulating platelets are reduced by one or more of the following processes: … philly charge stationsWebMar 1, 2024 · The probability of thrombocytopenia increases significantly at total trough valproate plasma concentrations above 110 mcg/mL in females and 135 mcg/mL in males. The benefit of improved seizure … tsa precheck age 14 tsa precheck age 13WebMar 1, 2024 · Propofol. Sodium Oxybate. Vorinostat. Warfarin. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. tsa precheck air new zealandWebMar 11, 2024 · People with thrombocytopenia can have excessive bleeding. This condition can occur in varying degrees. The risk of bleeding increases as the platelet count decreases. Thrombocytopenia can occur alone. Or, it can develop as a complication of another disease, such as cancer or a viral infection. tsa precheck alternatives