Paprotrain discover

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August undefined, 2024

WebPaprotrain is a reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (K = 3.4 μ M). Inhibits the basal ATPase activity of MKLP-2 (IC 50 = 1.35 μ M). … WebView and buy high purity Paprotrain from Tocris Bioscience, a Bio-Techne brand. Reversible inhibitor of MKLP-2. Skip to main content United States - (English) Country/Region selector. Please enter your country/region. Select Preferred Language. English. 简体中文 (800) 343-7475 ...

MKLP-2 Inhibitor, Paprotrain - Calbiochem MSDS - 512533

WebPaprotrain is a reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (K i = 3.4 μ M). Inhibits the basal ATPase activity of MKLP-2 (IC 50 = 1.35 μ M). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable. WebReversible inhibitor of MKLP-2 Shop Paprotrain, Tocris Bioscience™ at Fishersci.com Paprotrain, Tocris Bioscience, Quantity: 10 mg Fisher Scientific Fisher Scientific richards94rj gmail.com

New MKLP-2 inhibitors in the paprotrain series: Design, synthesis …

Nov 28, 2015 · WebBiological description. Selective cell-permeable MKLP-2 inhibitor. Reversible ATP-noncompetitive ATPase inhibitor (IC 50 values are 1.35 and 0.83 µM for basal and microtubule-stimulated activity respectively). Inhibits Aurora B. Induces cell cycle arrest at early metaphase I. WebCatalog No. Product Name Information Product Use Citations Product Validations; E0779 New: Paprotrain: Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.: E1180 New: Sovilnesib red marshmallows

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WebView or download the MKLP-2 Inhibitor, Paprotrain - Calbiochem MSDS (Material Safety Data Sheet) or SDS for 512533 from MilliporeSigma. WebApplication: Paprotrain is a cell-permeable inhibitor of the kinesin-6 family member KIF20A (MKLP-2) CAS Number: 57046-73-8 Purity: ≥98% Molecular Weight: 245.28 Molecular Formula: C 16 H 11 N 3 For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. * Refer to Certificate of Analysis for lot specific data (including water content). red marsh blackpoolWebJan 21, 2024 · The park entrance station is a booth that is located literally in the middle of the road. So once you get on Park Road 22, just keep going until you reach the end and … red marshmallow cereal

"WebThe MKLP-2 Inhibitor, Paprotrain controls the biological activity of MKLP-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. MKLP-2 Inhibitor, Paprotrain - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References Data Sheet " - Paprotrain discover

Paprotrain discover

Kinesin Inhibition Kinesin Inhibitor Review & List - selleckchem

WebPaderborn (German pronunciation: [paːdɐˈbɔʁn] (); Westphalian: Patterbuorn, also Paterboärn) is a city in eastern North Rhine-Westphalia, Germany, capital of the … WebBuy Paprotrain (CAS No. 57046-73-8) from Smolecule. Molecular Formula: C16H11N3. Molecular Weight: 245.28 g/mol. Selective cell-permeable MKLP-2 inhibitor.

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WebPaprotrain C16H11N3 - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National Institutes of Health WebFeb 15, 2016 · We have previously identified compound 1 (paprotrain) as the first selective inhibitor of MKLP-2. Herein we describe the synthesis and biological evaluation of new …

WebJul 18, 2014 · Paprotrain treatment and evaluation of embryos To evaluate the effect of KIF20A on embryo development, the Paprotrain stock solution was diluted with PZM-3 … WebFeb 15, 2016 · Paprotrain 1. Introduction Mitosis is a highly regulated process that separates the replicated sister chromatids equally into the daughter cells. One class of …

WebBELLA Italia Ristorante. 13848 Tilden Rd #192, Winter Garden, FL 34787. We were meeting old friends and wanted to share a long lunch reminiscing. The staff was wonderful in … WebJul 6, 2024 · The chromosomal passenger complex (CPC) participates in cytokinesis initiation by signaling from the spindle midzone and equatorial cortex [ 2], but the mechanisms underlying the anaphase-specific CPC localization are currently unresolved.

WebNov 29, 2016 · Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors Further investigation of Paprotrain: Towards the …

WebPaprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition … red marsh primary schoolMay 28, 2024 · red mars holdingWebMay 12, 2024 · A Leisurely Tour of Lake Arthur on Preston's Pearl. Preston's Pearl is named after the late Dr. Frank W. Preston whose conservation work led to the formation of the … richard saavedra obituaryWebPaprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. Paprotrain has been screened on … richardsa7 upmc.eduWebPaprotrain es un inhibidor permeable a las células de la quinesina MKLP-2, inhibe la actividad ATPasa de MKLP-2 con una IC50 de 1,35 μM y una Ki de 3,36 μM y muestra una actividad de inhibiciÓn moderada sobre DYRK1A con una IC50 de 5,5 μM. richard saarni medical historyWebApr 13, 2024 · Paprotrain (PAssenger PROteins TRAnsport INhibitor), is a cell permeable, reversible, ATP-uncompetitive inhibitor of the ATPase region of KIF20A. This inhibitor is … red marsh school calendarWebMay 7, 2024 · The suppression of endogenous KIF20A expression using small interfering ribonucleic acids or via treatment with paprotrain, a selective inhibitor of KIF20A, significantly inhibited breast cancer cell growth through cell cycle arrest at the G2/M phase and subsequent mitotic cell death. redmarsh roofing \u0026 timber